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Gα13 and Rho mediate endosomal trafficking of CXCR4 into Rab11+ vesicles upon SDF-1 stimulation
CXCR4, like other G protein coupled receptors (GPCRs), signals via heterotrimeric guanine nucleotide binding proteins (G proteins) to regulate gene transcription, migration, development, growth and transformation. We describe here a formerly-uncharacterized function of a G protein: a role in recepto...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057048/ https://ncbi.nlm.nih.gov/pubmed/21148034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002019 |
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