Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q− polycythemia vera

L3MBTL1, the human homolog of the Drosophila L(3)MBT polycomb group tumor suppressor gene, is located on chromosome 20q12, within the common deleted region identified in patients with 20q deletion-associated polycythemia vera, myelodysplastic syndrome, and acute myeloid leukemia. L3MBTL1 is expresse...

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Hlavní autoři: Perna, Fabiana, Gurvich, Nadia, Hoya-Arias, Ruben, Abdel-Wahab, Omar, Levine, Ross L., Asai, Takashi, Voza, Francesca, Menendez, Silvia, Wang, Lan, Liu, Fan, Zhao, Xinyang, Nimer, Stephen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974589/
https://ncbi.nlm.nih.gov/pubmed/20585043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-270611
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