The Need for Genetically Engineering Therapeutic Pluripotent Stem Cells

Por Sadelain, Michel
Publicado em 2010

CAR therapy: the CD19 paradigm

Por Sadelain, Michel
Publicado no J Clin Invest (2015)

A New Induction to the Gene and Cell Therapy Hall Of Fame: Genome Editing

Por Sadelain, Michel
Publicado no Mol Ther (2016)

Locus control region elements HS1 and HS4 enhance the therapeutic efficacy of globin gene transfer in β-thalassemic mice

Por Lisowski, Leszek, Sadelain, Michel
Publicado em 2007

The quest for spatio-temporal control of CAR T cells

Por Sun, Jie, Sadelain, Michel
Publicado no Cell Res (2015)

Combinatorial Antigen Targeting: Ideal Anti-tumor T-Cell Responses and Sensing

Por Themeli, Maria, Sadelain, Michel
Publicado no Trends Mol Med (2016)

IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell–mediated rejection of systemic lymphoma in immunodeficient mice

Por Markley, John C., Sadelain, Michel
Publicado em 2010

Reconstructing blood from induced pluripotent stem cells

Por Papapetrou, Eirini P, Sadelain, Michel
Publicado em 2010

Supplying Clotting Factors From Hematopoietic Stem Cell–derived Erythroid and Megakaryocytic Lineage Cells

Por Sadelain, Michel, Chang, Alex, Lisowski, Leszek
Publicado em 2009

The basic principles of chimeric antigen receptor (CAR) design

Por Sadelain, Michel, Brentjens, Renier, Riviere, Isabelle
Publicado em 2013

Mesothelin-Targeted CARs: Driving T cells to Solid Tumors

Por Morello, Aurore, Sadelain, Michel, Adusumilli, Prasad S.
Publicado no Cancer Discov (2015)

Retroviral Transduction of Murine Primary T Lymphocytes

Por Lee, James, Sadelain, Michel, Brentjens, Renier
Publicado no Methods Mol Biol (2009)

Hematopoietic stem cell engineering at a crossroads

Por Rivière, Isabelle, Dunbar, Cynthia E., Sadelain, Michel
Publicado em 2012

Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints

Por Janovitz, Tyler, Sadelain, Michel, Falck-Pedersen, Erik
Publicado em 2014

PD-1– and CTLA-4–Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses

Por Fedorov, Victor D., Themeli, Maria, Sadelain, Michel
Publicado no Sci Transl Med (2013)

LiPS-A3S, a human genomic site for robust expression of inserted transgenes

Por Kotini, Andriana G, Sadelain, Michel, Papapetrou, Eirini P
Publicado no Mol Ther Nucleic Acids (2016)

Erythroid-specific Human Factor IX Delivery From In Vivo Selected Hematopoietic Stem Cells Following Nonmyeloablative Conditioning in Hemophilia B Mice

Por Chang, Alex H, Stephan, Matthias T, Lisowski, Leszek, Sadelain, Michel
Publicado em 2008

The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion

Por Migliaccio, Anna Rita, Whitsett, Carolyn, Papayannopoulou, Thalia, Sadelain, Michel
Publicado em 2012

Highly Divergent Integration Profile of Adeno-Associated Virus Serotype 5 Revealed by High-Throughput Sequencing

Por Janovitz, Tyler, Oliveira, Thiago, Sadelain, Michel, Falck-Pedersen, Erik
Publicado em 2014

Cell and Gene Therapy for the Beta-Thalassemias: Advances and Prospects

Por Mansilla-Soto, Jorge, Riviere, Isabelle, Boulad, Farid, Sadelain, Michel
Publicado no Hum Gene Ther (2016)