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The quest for spatio-temporal control of CAR T cells
Chimeric antigen receptors (CARs) are synthetic receptors capable of directing potent antigen-specific anti-tumor T cell responses. A recent report by Wu et al. extends a series of strategies aiming to curb excessive T cell activity, utilizing in this instance a chemical dimerizer to aggregate antig...
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| Publicado no: | Cell Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670991/ https://ncbi.nlm.nih.gov/pubmed/26575974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.131 |
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