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CAR therapy: the CD19 paradigm

Twenty-five years after its inception, the genetic engineering of T cells is now a therapeutic modality pursued at an increasing number of medical centers. This immunotherapeutic strategy is predicated on gene transfer technology to instruct T lymphocytes to recognize and reject tumor cells. Chimeri...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autor principal: Sadelain, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588281/
https://ncbi.nlm.nih.gov/pubmed/26325036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80010
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