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Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

BACKGROUND: CD19-specific chimeric antigen receptor (CAR) T cells induce high rates of initial response among patients with relapsed B-cell acute lymphoblastic leukemia (ALL) and long-term remissions in a subgroup of patients. METHODS: We conducted a phase 1 trial involving adults with relapsed B-ce...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Park, Jae H., Rivière, Isabelle, Gonen, Mithat, Wang, Xiuyan, Sénéchal, Brigitte, Curran, Kevin J., Sauter, Craig, Wang, Yongzeng, Santomasso, Bianca, Mead, Elena, Roshal, Mikhail, Maslak, Peter, Davila, Marco, Brentjens, Renier J., Sadelain, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637939/
https://ncbi.nlm.nih.gov/pubmed/29385376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1709919
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