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How do CARs work?: Early insights from recent clinical studies targeting CD19
Second-generation chimeric antigen receptors (CARs) are powerful tools to redirect antigen-specific T cells independently of HLA-restriction. Recent clinical studies evaluating CD19-targeted T cells in patients with B-cell malignancies demonstrate the potency of CAR-engineered T cells. With results...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525612/ https://ncbi.nlm.nih.gov/pubmed/23264903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22524 |
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