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The promise and potential pitfalls of chimeric antigen receptors
One important purpose of T cell engineering is to generate tumor-targeted T cells through the genetic transfer of antigen-specific receptors, which consist of either physiological, MHC-restricted T cell receptors (TCRs) or non MHC-restricted chimeric antigen receptors (CARs). CARs combine antigen-sp...
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| Veröffentlicht in: | Curr Opin Immunol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548385/ https://ncbi.nlm.nih.gov/pubmed/19327974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.02.009 |
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