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Chimeric Antigen Receptors: A Cell and Gene Therapy Perspective

Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T lymphocytes to target chosen antigens. The targeting of CD19, a cell surface molecule expressed in the vast majority of leukemias and lymphomas, has been successfully translated in the clinic, earning CAR therapy a special di...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Rivière, Isabelle, Sadelain, Michel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417838/
https://ncbi.nlm.nih.gov/pubmed/28456379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.03.034
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