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Biology and clinical application of CAR T Cells for B cell malignancies

Chimeric antigen receptor (CAR)-modified T cells have generated broad interest in oncology following a series of dramatic clinical successes in patients with chemorefractory B cell malignancies. CAR therapy now appears to be on the cusp of regulatory approval as a cell-based immunotherapy. We review...

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Podrobná bibliografie
Vydáno v:Int J Hematol
Hlavní autoři: Davila, Marco L, Sadelain, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512169/
https://ncbi.nlm.nih.gov/pubmed/27262700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-016-2039-6
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