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Insight into next-generation CAR therapeutics: designing CAR T cells to improve clinical outcomes
Chimeric antigen receptor (CAR) T cell therapy has shown considerable promise for hematologic malignancies, leading to the US Food and Drug Administration approval of two CAR T cell–based therapies for the treatment of B cell acute lymphoblastic leukemia and large B cell lymphoma. Despite success in...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810492/ https://ncbi.nlm.nih.gov/pubmed/33463538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI142030 |
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