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CAR models: next-generation CAR modifications for enhanced T-cell function

T cells genetically targeted with a chimeric antigen receptor (CAR) to B-cell malignancies have demonstrated tremendous clinical outcomes. With the proof in principle for CAR T cells as a therapy for B-cell malignancies being established, current and future research is being focused on adapting CAR...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Abate-Daga, Daniel, Davila, Marco L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871190/
https://ncbi.nlm.nih.gov/pubmed/27231717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.14
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