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CAR models: next-generation CAR modifications for enhanced T-cell function
T cells genetically targeted with a chimeric antigen receptor (CAR) to B-cell malignancies have demonstrated tremendous clinical outcomes. With the proof in principle for CAR T cells as a therapy for B-cell malignancies being established, current and future research is being focused on adapting CAR...
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| Опубликовано в: : | Mol Ther Oncolytics |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871190/ https://ncbi.nlm.nih.gov/pubmed/27231717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.14 |
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