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IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell–mediated rejection of systemic lymphoma in immunodeficient mice

The γ(c)-cytokines are critical regulators of immunity and possess both overlapping and distinctive functions. However, comparative studies of their pleiotropic effects on human T cell–mediated tumor rejection are lacking. In a xenogeneic adoptive transfer model, we have compared the therapeutic pot...

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Detalhes bibliográficos
Main Authors: Markley, John C., Sadelain, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867264/
https://ncbi.nlm.nih.gov/pubmed/20190192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-241398
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