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Highly Divergent Integration Profile of Adeno-Associated Virus Serotype 5 Revealed by High-Throughput Sequencing

Adeno-associated virus serotype 5 (AAV-5) is a human parvovirus that infects a high percentage of the population. It is the most divergent AAV, the DNA sequence cleaved by the viral endonuclease is distinct from all other described serotypes and, uniquely, AAV-5 does not cross-complement the replica...

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Detalhes bibliográficos
Main Authors: Janovitz, Tyler, Oliveira, Thiago, Sadelain, Michel, Falck-Pedersen, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958079/
https://ncbi.nlm.nih.gov/pubmed/24335317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03419-13
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