Predictive chromatin signatures in the mammalian genome

Por Hon, Gary C., Hawkins, R. David, Ren, Bing
Publicado em 2009

Next-Generation Genomics: an Integrative Approach

Por Hawkins, R. David, Hon, Gary C., Ren, Bing
Publicado em 2010

cChIP-seq: a robust small-scale method for investigation of histone modifications

Por Valensisi, Cristina, Liao, Jo Ling, Andrus, Colin, Battle, Stephanie L., Hawkins, R. David
Publicado no BMC Genomics (2015)

Optimized detection of transcription factor-binding sites in ChIP-seq experiments

Por Elo, Laura L., Kallio, Aleksi, Laajala, Teemu D., Hawkins, R. David, Korpelainen, Eija, Aittokallio, Tero
Publicado em 2012

Extracting a low-dimensional description of multiple gene expression datasets reveals a potential driver for tumor-associated stroma in ovarian cancer

Por Celik, Safiye, Logsdon, Benjamin A., Battle, Stephanie, Drescher, Charles W., Rendi, Mara, Hawkins, R. David, Lee, Su-In
Publicado no Genome Med (2016)

Comprehensive identification and analysis of human accelerated regulatory DNA

Por Gittelman, Rachel M., Hun, Enna, Ay, Ferhat, Madeoy, Jennifer, Pennacchio, Len, Noble, William S., Hawkins, R. David, Akey, Joshua M.
Publicado no Genome Res (2015)

Identification of global regulators of T-helper cell lineage specification

Por Kanduri, Kartiek, Tripathi, Subhash, Larjo, Antti, Mannerström, Henrik, Ullah, Ubaid, Lund, Riikka, Hawkins, R. David, Ren, Bing, Lähdesmäki, Harri, Lahesmaa, Riitta
Publicado no Genome Med (2015)

Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia

Por Hawkins, R. David, Bashiardes, Stavros, Powder, Kara E., Sajan, Samin A., Bhonagiri, Veena, Alvarado, David M., Speck, Judith, Warchol, Mark E., Lovett, Michael
Publicado em 2007

Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

Por Bengtsson, Niclas E., Hall, John K., Odom, Guy L., Phelps, Michael P., Andrus, Colin R., Hawkins, R. David, Hauschka, Stephen D., Chamberlain, Joel R., Chamberlain, Jeffrey S.
Publicado no Nat Commun (2017)

An RNA Interference-Based Screen of Transcription Factor Genes Identifies Pathways Necessary for Sensory Regeneration in the Avian Inner Ear

Por Alvarado, David M., Hawkins, R. David, Bashiardes, Stavros, Veile, Rose A., Ku, Yuan-Chieh, Powder, Kara E., Spriggs, Meghan K., Speck, Judith D., Warchol, Mark E., Lovett, Michael
Publicado em 2011

Global Chromatin State Analysis Reveals Lineage-Specific Enhancers During the Initiation of Human T helper-1 and T helper-2 Cell Polarisation

Por Hawkins, R. David, Larjo, Antti, Tripathi, Subhash K., Wagner, Ulrich, Luu, Ying, Lönnberg, Tapio, Raghav, Sunil K., Lee, Leonard K., Lund, Riikka, Lähdesmäki, Harri, Ren, Bing, Lahesmaa, Riitta
Publicado no Immunity (2013)

Epigenetic Silencing of the Key Antioxidant Enzyme Catalase in Karyotypically Abnormal Human Pluripotent Stem Cells

Por Konki, Mikko, Pasumarthy, Kalyan, Malonzo, Maia, Sainio, Annele, Valensisi, Cristina, Söderström, Mirva, Emani, Maheswara Reddy, Stubb, Aki, Närvä, Elisa, Ghimire, Bishwa, Laiho, Asta, Järveläinen, Hannu, Lahesmaa, Riitta, Lähdesmäki, Harri, Hawkins, R. David, Lund, Riikka J.
Publicado no Sci Rep (2016)

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

Por Lister, Ryan, Pelizzola, Mattia, Kida, Yasuyuki S., Hawkins, R. David, Nery, Joseph R., Hon, Gary, Antosiewicz-Bourget, Jessica, O'Malley, Ronan, Castanon, Rosa, Klugman, Sarit, Downes, Michael, Yu, Ruth, Stewart, Ron, Ren, Bing, Thomson, James A., Evans, Ronald M., Ecker, Joseph R.
Publicado em 2011

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells

Por Kotini, Andriana G, Chang, Chan-Jung, Boussaad, Ibrahim, Delrow, Jeffrey J, Dolezal, Emily K, Nagulapally, Abhinav B, Perna, Fabiana, Fishbein, Gregory A, Klimek, Virginia M, Hawkins, R David, Huangfu, Danwei, Murry, Charles E, Graubert, Timothy, Nimer, Stephen D, Papapetrou, Eirini P
Publicado no Nat Biotechnol (2015)

Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential

Por Kyttälä, Aija, Moraghebi, Roksana, Valensisi, Cristina, Kettunen, Johannes, Andrus, Colin, Pasumarthy, Kalyan Kumar, Nakanishi, Mahito, Nishimura, Ken, Ohtaka, Manami, Weltner, Jere, Van Handel, Ben, Parkkonen, Olavi, Sinisalo, Juha, Jalanko, Anu, Hawkins, R. David, Woods, Niels-Bjarne, Otonkoski, Timo, Trokovic, Ras
Publicado no Stem Cell Reports (2016)

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

Por Hon, Gary C., Hawkins, R. David, Caballero, Otavia L., Lo, Christine, Lister, Ryan, Pelizzola, Mattia, Valsesia, Armand, Ye, Zhen, Kuan, Samantha, Edsall, Lee E., Camargo, Anamaria Aranha, Stevenson, Brian J., Ecker, Joseph R., Bafna, Vineet, Strausberg, Robert L., Simpson, Andrew J., Ren, Bing
Publicado em 2012

Human DNA methylomes at base resolution show widespread epigenomic differences

Por Lister, Ryan, Pelizzola, Mattia, Dowen, Robert H., Hawkins, R. David, Hon, Gary, Tonti-Filippini, Julian, Nery, Joseph R., Lee, Leonard, Ye, Zhen, Ngo, Que-Minh, Edsall, Lee, Antosiewicz-Bourget, Jessica, Stewart, Ron, Ruotti, Victor, Millar, A. Harvey, Thomson, James A., Ren, Bing, Ecker, Joseph R.
Publicado em 2009

Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency

Por Hawkins, R David, Hon, Gary C, Yang, Chuhu, Antosiewicz-Bourget, Jessica E, Lee, Leonard K, Ngo, Que-Minh, Klugman, Sarit, Ching, Keith A, Edsall, Lee E, Ye, Zhen, Kuan, Samantha, Yu, Pengzhi, Liu, Hui, Zhang, Xinmin, Green, Roland D, Lobanenkov, Victor V, Stewart, Ron, Thomson, James A, Ren, Bing
Publicado em 2011

Distinct Epigenomic Landscapes of Pluripotent and Lineage-committed Human Cells

Por Hawkins, R. David, Hon, Gary C., Lee, Leonard K., Ngo, QueMinh, Lister, Ryan, Pelizzola, Mattia, Edsall, Lee E., Kuan, Samantha, Luu, Ying, Klugman, Sarit, Antosiewicz-Bourget, Jessica, Ye, Zhen, Espinoza, Celso, Agarwahl, Saurabh, Shen, Li, Ruotti, Victor, Wang, Wei, Stewart, Ron, Thomson, James A., Ecker, Joseph R., Ren, Bing
Publicado em 2010

Derivation of naïve human embryonic stem cells

Por Ware, Carol B., Nelson, Angelique M., Mecham, Brigham, Hesson, Jennifer, Zhou, Wenyu, Jonlin, Erica C., Jimenez-Caliani, Antonio J., Deng, Xinxian, Cavanaugh, Christopher, Cook, Savannah, Tesar, Paul J., Okada, Jeffrey, Margaretha, Lilyana, Sperber, Henrik, Choi, Michael, Blau, C. Anthony, Treuting, Piper M., Hawkins, R. David, Cirulli, Vincenzo, Ruohola-Baker, Hannele
Publicado em 2014