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Distinct Epigenomic Landscapes of Pluripotent and Lineage-committed Human Cells

Human embryonic stem cells (hESCs) share an identical genome with lineage-committed cells, yet possess the remarkable properties of self-renewal and pluripotency. The diverse cellular properties in different cells have been attributed to their distinct epigenomes, but how much epigenomes differ rema...

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Detalhes bibliográficos
Main Authors: Hawkins, R. David, Hon, Gary C., Lee, Leonard K., Ngo, QueMinh, Lister, Ryan, Pelizzola, Mattia, Edsall, Lee E., Kuan, Samantha, Luu, Ying, Klugman, Sarit, Antosiewicz-Bourget, Jessica, Ye, Zhen, Espinoza, Celso, Agarwahl, Saurabh, Shen, Li, Ruotti, Victor, Wang, Wei, Stewart, Ron, Thomson, James A., Ecker, Joseph R., Ren, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867844/
https://ncbi.nlm.nih.gov/pubmed/20452322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.03.018
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