Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential

Reports on the retention of somatic cell memory in induced pluripotent stem cells (iPSCs) have complicated the selection of the optimal cell type for the generation of iPSC biobanks. To address this issue we compared transcriptomic, epigenetic, and differentiation propensities of genetically matched...

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Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Kyttälä, Aija, Moraghebi, Roksana, Valensisi, Cristina, Kettunen, Johannes, Andrus, Colin, Pasumarthy, Kalyan Kumar, Nakanishi, Mahito, Nishimura, Ken, Ohtaka, Manami, Weltner, Jere, Van Handel, Ben, Parkkonen, Olavi, Sinisalo, Juha, Jalanko, Anu, Hawkins, R. David, Woods, Niels-Bjarne, Otonkoski, Timo, Trokovic, Ras
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750096/
https://ncbi.nlm.nih.gov/pubmed/26777058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.12.009
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