Identification of global regulators of T-helper cell lineage specification

BACKGROUND: Activation and differentiation of T-helper (Th) cells into Th1 and Th2 types is a complex process orchestrated by distinct gene activation programs engaging a number of genes. This process is crucial for a robust immune response and an imbalance might lead to disease states such as autoi...

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Vydáno v:Genome Med
Hlavní autoři: Kanduri, Kartiek, Tripathi, Subhash, Larjo, Antti, Mannerström, Henrik, Ullah, Ubaid, Lund, Riikka, Hawkins, R. David, Ren, Bing, Lähdesmäki, Harri, Lahesmaa, Riitta
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654807/
https://ncbi.nlm.nih.gov/pubmed/26589177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0237-0
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