Global Chromatin State Analysis Reveals Lineage-Specific Enhancers During the Initiation of Human T helper-1 and T helper-2 Cell Polarisation

Naïve CD4(+) T cells can differentiate into specific helper and regulatory T cell lineages in order to combat infection and disease. The correct response to cytokines and a controlled balance of these populations is critical for the immune system and the avoidance of autoimmune disorders. To investi...

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Dettagli Bibliografici
Pubblicato in:Immunity
Autori principali: Hawkins, R. David, Larjo, Antti, Tripathi, Subhash K., Wagner, Ulrich, Luu, Ying, Lönnberg, Tapio, Raghav, Sunil K., Lee, Leonard K., Lund, Riikka, Lähdesmäki, Harri, Ren, Bing, Lahesmaa, Riitta
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607036/
https://ncbi.nlm.nih.gov/pubmed/23791644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.05.011
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