An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation

BACKGROUND: A proper balance between different T helper (Th) cell subsets is necessary for normal functioning of the adaptive immune system. Revealing key genes and pathways driving the differentiation to distinct Th cell lineages provides important insight into underlying molecular mechanisms and n...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Äijö, Tarmo, Edelman, Sanna M, Lönnberg, Tapio, Larjo, Antti, Kallionpää, Henna, Tuomela, Soile, Engström, Emilia, Lahesmaa, Riitta, Lähdesmäki, Harri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526425/
https://ncbi.nlm.nih.gov/pubmed/23110343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-572
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