An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation

BACKGROUND: A proper balance between different T helper (Th) cell subsets is necessary for normal functioning of the adaptive immune system. Revealing key genes and pathways driving the differentiation to distinct Th cell lineages provides important insight into underlying molecular mechanisms and n...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Äijö, Tarmo, Edelman, Sanna M, Lönnberg, Tapio, Larjo, Antti, Kallionpää, Henna, Tuomela, Soile, Engström, Emilia, Lahesmaa, Riitta, Lähdesmäki, Harri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526425/
https://ncbi.nlm.nih.gov/pubmed/23110343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-572
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