Derivation of naïve human embryonic stem cells

The naïve pluripotent state has been shown in mice to lead to broad and more robust developmental potential relative to primed mouse epiblast cells. The human naïve ES cell state has eluded derivation without the use of transgenes, and forced expression of OCT4, KLF4, and KLF2 allows maintenance of...

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Bibliografische gegevens
Hoofdauteurs: Ware, Carol B., Nelson, Angelique M., Mecham, Brigham, Hesson, Jennifer, Zhou, Wenyu, Jonlin, Erica C., Jimenez-Caliani, Antonio J., Deng, Xinxian, Cavanaugh, Christopher, Cook, Savannah, Tesar, Paul J., Okada, Jeffrey, Margaretha, Lilyana, Sperber, Henrik, Choi, Michael, Blau, C. Anthony, Treuting, Piper M., Hawkins, R. David, Cirulli, Vincenzo, Ruohola-Baker, Hannele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970494/
https://ncbi.nlm.nih.gov/pubmed/24623855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319738111
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