Derivation of naïve human embryonic stem cells

The naïve pluripotent state has been shown in mice to lead to broad and more robust developmental potential relative to primed mouse epiblast cells. The human naïve ES cell state has eluded derivation without the use of transgenes, and forced expression of OCT4, KLF4, and KLF2 allows maintenance of...

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主要な著者: Ware, Carol B., Nelson, Angelique M., Mecham, Brigham, Hesson, Jennifer, Zhou, Wenyu, Jonlin, Erica C., Jimenez-Caliani, Antonio J., Deng, Xinxian, Cavanaugh, Christopher, Cook, Savannah, Tesar, Paul J., Okada, Jeffrey, Margaretha, Lilyana, Sperber, Henrik, Choi, Michael, Blau, C. Anthony, Treuting, Piper M., Hawkins, R. David, Cirulli, Vincenzo, Ruohola-Baker, Hannele
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970494/
https://ncbi.nlm.nih.gov/pubmed/24623855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319738111
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