Network Pharmacology Strategies Toward Multi-Target Anticancer Therapies: From Computational Models to Experimental Design Principles

Por Tang, Jing, Aittokallio, Tero
Publicado em 2014

Genetic variants and their interactions in disease risk prediction – machine learning and network perspectives

Por Okser, Sebastian, Pahikkala, Tapio, Aittokallio, Tero
Publicado em 2013

What is synergy? The Saariselkä agreement revisited

Por Tang, Jing, Wennerberg, Krister, Aittokallio, Tero
Publicado no Front Pharmacol (2015)

Medroxyprogesterone improves nocturnal breathing in postmenopausal women with chronic obstructive pulmonary disease

Por Saaresranta, Tarja, Aittokallio, Tero, Utriainen, Karri, Polo, Olli
Publicado em 2005

A statistical score for assessing the quality of multiple sequence alignments

Por Ahola, Virpi, Aittokallio, Tero, Vihinen, Mauno, Uusipaikka, Esa
Publicado em 2006

Quantitative maps of genetic interactions in yeast - Comparative evaluation and integrative analysis

Por Lindén, Rolf O, Eronen, Ville-Pekka, Aittokallio, Tero
Publicado em 2011

TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples

Por He, Liye, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing
Publicado no Bioinformatics (2015)

Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

Por Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing
Publicado no Comput Struct Biotechnol J (2015)

Missing value imputation improves clustering and interpretation of gene expression microarray data

Por Tuikkala, Johannes, Elo, Laura L, Nevalainen, Olli S, Aittokallio, Tero
Publicado em 2008

Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies

Por Laajala, Essi, Aittokallio, Tero, Lahesmaa, Riitta, Elo, Laura L
Publicado em 2009

Predicting Quantitative Genetic Interactions by Means of Sequential Matrix Approximation

Por Järvinen, Aki P., Hiissa, Jukka, Elo, Laura L., Aittokallio, Tero
Publicado em 2008

A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization

Por Tuikkala, Johannes, Vähämaa, Heidi, Salmela, Pekka, Nevalainen, Olli S, Aittokallio, Tero
Publicado em 2012

Wrapper-based selection of genetic features in genome-wide association studies through fast matrix operations

Por Pahikkala, Tapio, Okser, Sebastian, Airola, Antti, Salakoski, Tapio, Aittokallio, Tero
Publicado em 2012

PhosFox: a bioinformatics tool for peptide-level processing of LC-MS/MS-based phosphoproteomic data

Por Söderholm, Sandra, Hintsanen, Petteri, Öhman, Tiina, Aittokallio, Tero, Nyman, Tuula A
Publicado em 2014

Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices

Por Eronen, Ville-Pekka, Lindén, Rolf O., Lindroos, Anna, Kanerva, Mirella, Aittokallio, Tero
Publicado em 2010

Regularized Machine Learning in the Genetic Prediction of Complex Traits

Por Okser, Sebastian, Pahikkala, Tapio, Airola, Antti, Salakoski, Tapio, Ripatti, Samuli, Aittokallio, Tero
Publicado no PLoS Genet (2014)

Integrating probe-level expression changes across generations of Affymetrix arrays

Por Elo, Laura L., Lahti, Leo, Skottman, Heli, Kyläniemi, Minna, Lahesmaa, Riitta, Aittokallio, Tero
Publicado em 2005

A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments

Por Laajala, Teemu D, Raghav, Sunil, Tuomela, Soile, Lahesmaa, Riitta, Aittokallio, Tero, Elo, Laura L
Publicado em 2009

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Por Tang, Jing, Karhinen, Leena, Xu, Tao, Szwajda, Agnieszka, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero
Publicado em 2013

Toward more realistic drug–target interaction predictions

Por Pahikkala, Tapio, Airola, Antti, Pietilä, Sami, Shakyawar, Sushil, Szwajda, Agnieszka, Tang, Jing, Aittokallio, Tero
Publicado no Brief Bioinform (2015)