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Predicting Quantitative Genetic Interactions by Means of Sequential Matrix Approximation

Despite the emerging experimental techniques for perturbing multiple genes and measuring their quantitative phenotypic effects, genetic interactions have remained extremely difficult to predict on a large scale. Using a recent high-resolution screen of genetic interactions in yeast as a case study,...

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Detalhes bibliográficos
Main Authors: Järvinen, Aki P., Hiissa, Jukka, Elo, Laura L., Aittokallio, Tero
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538561/
https://ncbi.nlm.nih.gov/pubmed/18818762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003284
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