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Predicting Quantitative Genetic Interactions by Means of Sequential Matrix Approximation
Despite the emerging experimental techniques for perturbing multiple genes and measuring their quantitative phenotypic effects, genetic interactions have remained extremely difficult to predict on a large scale. Using a recent high-resolution screen of genetic interactions in yeast as a case study,...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538561/ https://ncbi.nlm.nih.gov/pubmed/18818762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003284 |
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