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Genetic variants and their interactions in disease risk prediction – machine learning and network perspectives

A central challenge in systems biology and medical genetics is to understand how interactions among genetic loci contribute to complex phenotypic traits and human diseases. While most studies have so far relied on statistical modeling and association testing procedures, machine learning and predicti...

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Autors principals: Okser, Sebastian, Pahikkala, Tapio, Aittokallio, Tero
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606427/
https://ncbi.nlm.nih.gov/pubmed/23448398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-6-5
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