Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices

Recent technological developments in genetic screening approaches have offered the means to start exploring quantitative genotype-phenotype relationships on a large-scale. What remains unclear is the extent to which the quantitative genetic interaction datasets can distinguish the broad spectrum of...

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Bibliographic Details
Main Authors: Eronen, Ville-Pekka, Lindén, Rolf O., Lindroos, Anna, Kanerva, Mirella, Aittokallio, Tero
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904709/
https://ncbi.nlm.nih.gov/pubmed/20657656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011611
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