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Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices

Recent technological developments in genetic screening approaches have offered the means to start exploring quantitative genotype-phenotype relationships on a large-scale. What remains unclear is the extent to which the quantitative genetic interaction datasets can distinguish the broad spectrum of...

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Detalhes bibliográficos
Main Authors: Eronen, Ville-Pekka, Lindén, Rolf O., Lindroos, Anna, Kanerva, Mirella, Aittokallio, Tero
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904709/
https://ncbi.nlm.nih.gov/pubmed/20657656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011611
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