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Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices

Recent technological developments in genetic screening approaches have offered the means to start exploring quantitative genotype-phenotype relationships on a large-scale. What remains unclear is the extent to which the quantitative genetic interaction datasets can distinguish the broad spectrum of...

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Hlavní autoři: Eronen, Ville-Pekka, Lindén, Rolf O., Lindroos, Anna, Kanerva, Mirella, Aittokallio, Tero
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904709/
https://ncbi.nlm.nih.gov/pubmed/20657656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011611
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