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Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

A recent trend in drug development is to identify drug combinations or multi-target agents that effectively modify multiple nodes of disease-associated networks. Such polypharmacological effects may reduce the risk of emerging drug resistance by means of attacking the disease networks through synerg...

詳細記述

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書誌詳細
主要な著者: Tang, Jing, Karhinen, Leena, Xu, Tao, Szwajda, Agnieszka, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772058/
https://ncbi.nlm.nih.gov/pubmed/24068907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003226
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