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From drug response profiling to target addiction scoring in cancer cell models
Deconvoluting the molecular target signals behind observed drug response phenotypes is an important part of phenotype-based drug discovery and repurposing efforts. We demonstrate here how our network-based deconvolution approach, named target addiction score (TAS), provides insights into the functio...
Gorde:
| Argitaratua izan da: | Dis Model Mech |
|---|---|
| Egile Nagusiak: | , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Company of Biologists
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610238/ https://ncbi.nlm.nih.gov/pubmed/26438695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.021105 |
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