The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal and leukemia cells

N(6)-methyladenosine (m(6)A) is an abundant nucleotide modification in mRNA that is required for the differentiation of mouse embryonic stem cells. However, it remains unknown whether m(6)A controls differentiation of normal and/or malignant myeloid hematopoietic cells. Here we show that shRNA-media...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Vu, Ly P., Pickering, Brian F., Cheng, Yuanming, Zaccara, Sara, Nguyen, Diu, Minuesa, Gerard, Chou, Timothy, Chow, Arthur, Saletore, Yogesh, MacKay, Matthew, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Klimek, Virginia M., Garrett-Bakelman, Francine E., Melnick, Ari, Carroll, Martin, Mason, Christopher E., Jaffrey, Samie R., Kharas, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677536/
https://ncbi.nlm.nih.gov/pubmed/28920958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4416
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados