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MSI2 is required for maintaining activated myelodysplastic syndrome stem cells
Myelodysplastic syndromes (MDS) are driven by complex genetic and epigenetic alterations. The MSI2 RNA-binding protein has been demonstrated to have a role in acute myeloid leukaemia and stem cell function, but its role in MDS is unknown. Here, we demonstrate that elevated MSI2 expression correlates...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764878/ https://ncbi.nlm.nih.gov/pubmed/26898884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10739 |
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