Guide to Interpreting Disease Responses in Chronic Myeloid Leukemia

Por Galinsky, Ilene, Buchanan, Susan
Publicado em 2012

Combining the FLT3 Inhibitor PKC412 and the Triterpenoid CDDO-Me Synergistically Induces Apoptosis in Acute Myeloid Leukemia with ITD mutation

Por Ahmad, Rehan, Liu, Suiyang, Weisberg, Ellen, Nelson, Erik, Galinsky, Ilene, Meyer, Colin, Kufe, Donald, Kharbanda, Surender, Stone, Richard
Publicado em 2010

A Phase II Study of the EGFR inhibitor gefitinib in patients with acute myeloid leukemia

Por DeAngelo, Daniel J., Neuberg, Donna, Amrein, Philip C., Berchuck, Jacob, Wadleigh, Martha, Sirulnik, L. Andres, Galinsky, Ilene, Golub, Todd, Stegmaier, Kimberly, Stone, Richard M.
Publicado no Leuk Res (2013)

Identification of AML1-ETO modulators by chemical genomics

Por Corsello, Steven M., Roti, Giovanni, Ross, Kenneth N., Chow, Kwan T., Galinsky, Ilene, DeAngelo, Daniel J., Stone, Richard M., Kung, Andrew L., Golub, Todd R., Stegmaier, Kimberly
Publicado em 2009

High Dose Cytarabine plus Gemtuzumab Ozogamicin for Patients with Relapsed or Refractory Acute Myeloid Leukemia: Cancer and Leukemia Group B Study 19902

Por Stone, Richard M., Moser, Barry, Sanford, Ben, Schulman, Philip, Kolitz, Jonathan E., Allen, Steven, Stock, Wendy, Galinsky, Ilene, Vij, Ravi, Marcucci, Guido, Hurd, David, Larson, Richard A.
Publicado em 2010

Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells

Por Weisberg, Ellen, Wright, Renee D., McMillin, Douglas W., Mitsiades, Constantine, Ray, Arghya, Barrett, Rosemary, Adamia, Sophia, Stone, Richard, Galinsky, Ilene, Kung, Andrew L., Griffin, James D.
Publicado em 2008

Small molecule inhibitors of USP1 target ID1 degradation in leukemic cells

Por Mistry, Helena, Hsieh, Grace, Buhrlage, Sara J., Huang, Min, Park, Eunmi, Cuny, Gregory D., Galinsky, Ilene, Stone, Richard M, Gray, Nathanael S., D'Andrea, Alan D., Parmar, Kalindi
Publicado em 2013

Non-hematologic predictors of mortality improve the prognostic value of the international prognostic scoring system for MDS in older adults()

Por Fega, K. Rebecca, Abel, Gregory A., Motyckova, Gabriela, Sherman, Alexander E., DeAngelo, Daniel J., Steensma, David P., Galinsky, Ilene, Wadleigh, Martha, Stone, Richard M., Driver, Jane A.
Publicado no J Geriatr Oncol (2015)

Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia

Por Bhola, Patrick D., Mar, Brenton G., Lindsley, R. Coleman, Ryan, Jeremy A., Hogdal, Leah J., Vo, Thanh Trang, DeAngelo, Daniel J., Galinsky, Ilene, Ebert, Benjamin L., Letai, Anthony
Publicado no J Clin Invest (2016)

Outcome of older adults with cytogenetically normal AML (CN-AML) and FLT3 mutations

Por Singh, Harshabad, Asali, Salma, Werner, Lillian L., DeAngelo, Daniel J., Ballen, Karen K., Amrein, Philip C., Wadleigh, Martha, Galinsky, Ilene, Neuberg, Donna S., Fox, Edward A., Stone, Richard M., Attar, Eyal C.
Publicado em 2011

Selective Akt Inhibitors Synergize with Tyrosine Kinase Inhibitors and Effectively Override Stroma-Associated Cytoprotection of Mutant FLT3-Positive AML Cells

Por Weisberg, Ellen, Liu, Qingsong, Zhang, Xin, Nelson, Erik, Sattler, Martin, Liu, Feiyang, Nicolais, Maria, Zhang, Jianming, Mitsiades, Constantine, Smith, Robert W., Stone, Richard, Galinsky, Ilene, Nonami, Atsushi, Griffin, James D., Gray, Nathanael
Publicado em 2013

Smac mimetics: implications for enhancement of targeted therapies in leukemia: Treating leukemia with Smac mimetics

Por Weisberg, Ellen, Ray, Arghya, Barrett, Rosemary, Nelson, Erik, Christie, Amanda, Porter, Dale, Straub, Christopher, Zawel, Leigh, Daley, John F., Lazo-Kallanian, Suzan, Stone, Richard, Galinsky, Ilene, Frank, David, Kung, Andrew L., Griffin, James D.
Publicado em 2010

Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors

Por Levis, Mark, Brown, Patrick, Smith, B. Douglas, Stine, Adam, Pham, Rosalyn, Stone, Richard, DeAngelo, Daniel, Galinsky, Ilene, Giles, Frank, Estey, Elihu, Kantarjian, Hagop, Cohen, Pamela, Wang, Yanfeng, Roesel, Johannes, Karp, Judith E., Small, Donald
Publicado em 2006

Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL– and mutant FLT3-expressing cells

Por Weisberg, Ellen, Banerji, Lolita, Wright, Renee D., Barrett, Rosemary, Ray, Arghya, Moreno, Daisy, Catley, Laurence, Jiang, Jingrui, Hall-Meyers, Elizabeth, Sauveur-Michel, Maira, Stone, Richard, Galinsky, Ilene, Fox, Edward, Kung, Andrew L., Griffin, James D.
Publicado em 2008

Comparison of autologous stem cell transplantation versus consolidation chemotherapy for patients with cytogenetically normal acute myeloid leukemia and FLT3ITD

Por Singh, Harshabad, Werner, Lillian L, Asali, Salma, DeAngelo, Daniel J, Ballen, Karen K, Amrein, Philip C, Wadleigh, Martha, Galinsky, Ilene, Wolpin, Brian, Pidala, Joseph, Neuberg, Donna S, Fox, Edward A, Stone, Richard M, Attar, Eyal C
Publicado em 2011

Discovery and Characterization of Novel Mutant FLT3 Kinase Inhibitors

Por Weisberg, Ellen, Geun Choi, Hwan, Barrett, Rosemary, Zhou, Wenjun, Zhang, Jianming, Ray, Arghya, Nelson, Erik A., Jiang, Jingrui, Moreno, Daisy, Stone, Richard, Galinsky, Ilene, Fox, Edward, Adamia, Sophia, Kung, Andrew L., Gray, Nathanael S., Griffin, James D.
Publicado em 2010

Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells

Por Bhanot, Haymanti, Reddy, Mamatha M., Nonami, Atsushi, Weisberg, Ellen L., Bonal, Dennis, Kirschmeier, Paul T., Salgia, Sabrina, Podar, Klaus, Galinsky, Ilene, Chowdary, Tirumala K., Neuberg, Donna, Tonon, Giovanni, Stone, Richard M., Asara, John, Griffin, James D., Sattler, Martin
Publicado no Leukemia (2015)

Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: Synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors, and JAK...

Por Weisberg, Ellen, Liu, Qingsong, Nelson, Erik, Kung, Andrew L., Christie, Amanda L., Bronson, Rod, Sattler, Martin, Sanda, Takaomi, Zhao, Zheng, Hur, Wooyoung, Mitsiades, Constantine, Smith, Robert, Daley, John F., Stone, Richard, Galinsky, Ilene, Griffin, James D., Gray, Nathanael
Publicado em 2012

Implementing a Geriatric Assessment in Cooperative Group Clinical Cancer Trials: CALGB 360401

Por Hurria, Arti, Cirrincione, Constance T., Muss, Hyman B., Kornblith, Alice B., Barry, William, Artz, Andrew S., Schmieder, Linda, Ansari, Rafat, Tew, William P., Weckstein, Douglas, Kirshner, Jeffrey, Togawa, Kayo, Hansen, Kurt, Katheria, Vani, Stone, Richard, Galinsky, Ilene, Postiglione, John, Cohen, Harvey Jay
Publicado em 2011

MUC1 IS A POTENTIAL TARGET FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA STEM CELLS

Por Stroopinsky, Dina, Rosenblatt, Jacalyn, Ito, Keisuke, Mills, Heidi, Yin, Li, Rajabi, Hasan, Vasir, Baldev, Kufe, Turner, Luptakova, Katarina, Arnason, Jon, Nardella, Caterina, Levine, James D., Joyce, Robin, Galinsky, Ilene, Reiter, Yoram, Stone, Richard, Pandolfi, Pier Paolo, Kufe, Donald, Avigan, David
Publicado em 2013