Awakening the Hippo co-activator YAP1, a mercurial cancer gene, in hematologic cancers

Por Cottini, Francesca, Anderson, Kenneth C, Tonon, Giovanni
Publicado no Mol Cell Oncol (2014)

Stable Karyotypes in Epithelial Cancer Cell Lines Despite High Rates of Ongoing Structural and Numerical Chromosomal Instability

Por Roschke, Anna V, Stover, Kristen, Tonon, Giovanni, Schäffer, Alejandro A, Kirsch, Ilan R
Publicado em 2002

A Study of MECT1-MAML2 in Mucoepidermoid Carcinoma and Warthin’s Tumor of Salivary Glands

Por Martins, Carmo, Cavaco, Branca, Tonon, Giovanni, Kaye, Frederic J., Soares, Jorge, Fonseca, Isabel
Publicado em 2004

Bone Marrow Endosteal Mesenchymal Progenitors Depend on HIF Factors for Maintenance and Regulation of Hematopoiesis

Por Guarnerio, Jlenia, Coltella, Nadia, Ala, Ugo, Tonon, Giovanni, Pandolfi, Pier Paolo, Bernardi, Rosa
Publicado em 2014

Karyotypic “state” as a potential determinant for anticancer drug discovery

Por Roschke, Anna V., Lababidi, Samir, Tonon, Giovanni, Gehlhaus, Kristen S., Bussey, Kimberly, Weinstein, John N., Kirsch, Ilan R.
Publicado em 2005

Iron increases the susceptibility of multiple myeloma cells to bortezomib

Por Campanella, Alessandro, Santambrogio, Paolo, Fontana, Francesca, Frenquelli, Michela, Cenci, Simone, Marcatti, Magda, Sitia, Roberto, Tonon, Giovanni, Camaschella, Clara
Publicado em 2013

Synthetic lethal approaches exploiting DNA damage in aggressive myeloma

Por Cottini, Francesca, Hideshima, Teru, Suzuki, Rikio, Tai, Yu-Tzu, Bianchini, Giampaolo, Richardson, Paul G., Anderson, Kenneth C., Tonon, Giovanni
Publicado no Cancer Discov (2015)

H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing

Por Rondinelli, Beatrice, Schwerer, Hélène, Antonini, Elena, Gaviraghi, Marco, Lupi, Alessio, Frenquelli, Michela, Cittaro, Davide, Segalla, Simona, Lemaitre, Jean-Marc, Tonon, Giovanni
Publicado no Nucleic Acids Res (2015)

Structural basis for PHD(V)C5HCH(NSD1)–C2HR(Nizp1) interaction: implications for Sotos syndrome

Por Berardi, Andrea, Quilici, Giacomo, Spiliotopoulos, Dimitrios, Corral-Rodriguez, Maria Angeles, Martin-Garcia, Fernando, Degano, Massimo, Tonon, Giovanni, Ghitti, Michela, Musco, Giovanna
Publicado no Nucleic Acids Res (2016)

Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival

Por Di Lullo, Giulia, Marcatti, Magda, Heltai, Silvia, Brunetto, Emanuela, Tresoldi, Cristina, Bondanza, Attilio, Bonini, Chiara, Ponzoni, Maurilio, Tonon, Giovanni, Ciceri, Fabio, Bordignon, Claudio, Protti, Maria Pia
Publicado no Oncoimmunology (2015)

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias

Por Lionetti, Marta, Barbieri, Marzia, Todoerti, Katia, Agnelli, Luca, Fabris, Sonia, Tonon, Giovanni, Segalla, Simona, Cifola, Ingrid, Pinatel, Eva, Tassone, Pierfrancesco, Musto, Pellegrino, Baldini, Luca, Neri, Antonino
Publicado no Oncotarget (2015)

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA

Por Segalla, Simona, Pivetti, Silvia, Todoerti, Katia, Chudzik, Malgorzata Agata, Giuliani, Erica Claudia, Lazzaro, Federico, Volta, Viviana, Lazarevic, Dejan, Musco, Giovanna, Muzi-Falconi, Marco, Neri, Antonino, Biffo, Stefano, Tonon, Giovanni
Publicado no Nucleic Acids Res (2015)

Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma

Por Calcinotto, Arianna, Ponzoni, Maurilio, Ria, Roberto, Grioni, Matteo, Cattaneo, Elena, Villa, Isabella, Sabrina Bertilaccio, Maria Teresa, Chesi, Marta, Rubinacci, Alessandro, Tonon, Giovanni, Bergsagel, P Leif, Vacca, Angelo, Bellone, Matteo
Publicado no Oncoimmunology (2015)

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) p...

Por Calura, Enrica, Bisognin, Andrea, Manzoni, Martina, Todoerti, Katia, Taiana, Elisa, Sales, Gabriele, Morgan, Gareth J., Tonon, Giovanni, Amodio, Nicola, Tassone, Pierfrancesco, Neri, Antonino, Agnelli, Luca, Romualdi, Chiara, Bortoluzzi, Stefania
Publicado no Oncotarget (2015)

The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

Por Podar, Klaus, Tonon, Giovanni, Sattler, Martin, Tai, Yu-Tzu, LeGouill, Steven, Yasui, Hiroshi, Ishitsuka, Kenji, Kumar, Shaji, Kumar, Rakesh, Pandite, Lini N., Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C.
Publicado em 2006

Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling

Por Raab, Marc S., Breitkreutz, Iris, Tonon, Giovanni, Zhang, Jing, Hayden, Patrick J., Nguyen, Thu, Fruehauf, Johannes H., Lin, Boris K., Chauhan, Dharminder, Hideshima, Teru, Munshi, Nikhil C., Anderson, Kenneth C., Podar, Klaus
Publicado em 2009

p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

Por Memmi, Elisa Maria, Sanarico, Anna Giulia, Giacobbe, Arianna, Peschiaroli, Angelo, Frezza, Valentina, Cicalese, Angelo, Pisati, Federica, Tosoni, Daniela, Zhou, Huiqing, Tonon, Giovanni, Antonov, Alexey, Melino, Gerry, Pelicci, Pier Giuseppe, Bernassola, Francesca
Publicado no Proc Natl Acad Sci U S A (2015)

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

Por Lionetti, Marta, Barbieri, Marzia, Todoerti, Katia, Agnelli, Luca, Marzorati, Simona, Fabris, Sonia, Ciceri, Gabriella, Galletti, Serena, Milesi, Giulia, Manzoni, Martina, Mazzoni, Mara, Greco, Angela, Tonon, Giovanni, Musto, Pellegrino, Baldini, Luca, Neri, Antonino
Publicado no Oncotarget (2015)

Insight On Colorectal Carcinoma Infiltration by Studying Perilesional Extracellular Matrix

Por Nebuloni, Manuela, Albarello, Luca, Andolfo, Annapaola, Magagnotti, Cinzia, Genovese, Luca, Locatelli, Irene, Tonon, Giovanni, Longhi, Erika, Zerbi, Pietro, Allevi, Raffaele, Podestà, Alessandro, Puricelli, Luca, Milani, Paolo, Soldarini, Armando, Salonia, Andrea, Alfano, Massimo
Publicado no Sci Rep (2016)

High-resolution genomic profiles of human lung cancer

Por Tonon, Giovanni, Wong, Kwok-Kin, Maulik, Gautam, Brennan, Cameron, Feng, Bin, Zhang, Yunyu, Khatry, Deepak B., Protopopov, Alexei, You, Mingjian James, Aguirre, Andrew J., Martin, Eric S., Yang, Zhaohui, Ji, Hongbin, Chin, Lynda, DePinho, Ronald A.
Publicado em 2005