Overcoming Tyrosine Kinase Inhibitor Resistance in Transformed Cell Harboring SEPT9-ABL1 Chimeric Fusion Protein

Por Kawai, Hidetsugu, Matsushita, Hiromichi, Suzuki, Rikio, Kitamura, Yuka, Ogawa, Yoshiaki, Kawada, Hiroshi, Ando, Kiyoshi
Publicado no Neoplasia (2019)

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma

Por Suzuki, Rikio, Kitamura, Yuka, Nakamura, Yoshihiko, Akashi, Hibiki, Ogawa, Yoshiaki, Kawada, Hiroshi, Ando, Kiyoshi
Publicado no Oncotarget (2020)

Jagged1-induced Notch activation contributes to the acquisition of bortezomib resistance in myeloma cells

Por Muguruma, Yukari, Yahata, Takashi, Warita, Takayuki, Hozumi, Katsuto, Nakamura, Yoshihiko, Suzuki, Rikio, Ito, Mamoru, Ando, Kiyoshi
Publicado no Blood Cancer J (2017)

Identification of a novel SEPT9-ABL1 fusion gene in a patient with T-cell prolymphocytic leukemia

Por Suzuki, Rikio, Matsushita, Hiromochi, Kawai, Hidetsugu, Matsuzawa, Hideyuki, Tsuboi, Kosuke, Watanabe, Shigeki, Kawada, Hiroshi, Ogawa, Yoshiaki, Ando, Kiyoshi
Publicado em 2014

Synthetic lethal approaches exploiting DNA damage in aggressive myeloma

Por Cottini, Francesca, Hideshima, Teru, Suzuki, Rikio, Tai, Yu-Tzu, Bianchini, Giampaolo, Richardson, Paul G., Anderson, Kenneth C., Tonon, Giovanni
Publicado no Cancer Discov (2015)

Phase 1 study of tazemetostat in Japanese patients with relapsed or refractory B‐cell lymphoma

Por Munakata, Wataru, Shirasugi, Yukari, Tobinai, Kensei, Onizuka, Makoto, Makita, Shinichi, Suzuki, Rikio, Maruyama, Dai, Kawai, Hidetsugu, Izutsu, Koji, Nakanishi, Tadashi, Shiba, Sari, Hojo, Seichiro, Ando, Kiyoshi
Publicado no Cancer Sci (2021)

Clinicopathological evaluation of methotrexate-associated lymphoproliferative disorders with special focus on Epstein-Barr virus-positive mucocutaneous lesions

Por Shiraiwa, Sawako, Kikuti, Yara Yukie, Carreras, Joaquim, Hara, Ryujiro, Aoyama, Yasuyuki, Ogiya, Daisuke, Suzuki, Rikio, Toyosaki, Masako, Ohmachi, Ken, Ogawa, Yoshiaki, Kawada, Hiroshi, Sato, Shinji, Nakamura, Naoya, Ando, Kiyoshi
Publicado no J Clin Exp Hematop (2020)

Refractory acute promyelocytic leukemia successfully treated with combination therapy of arsenic trioxide and tamibarotene: A case report

Por Kojima, Minoru, Ogiya, Daisuke, Ichiki, Akifumi, Hara, Ryujiro, Amaki, Jun, Kawai, Hidetsugu, Numata, Hiroki, Sato, Ai, Miyamoto, Mitsuki, Suzuki, Rikio, Machida, Shinichiro, Matsushita, Hiromichi, Ogawa, Yoshiaki, Kawada, Hiroshi, Ando, Kiyoshi
Publicado no Leuk Res Rep (2016)

Small Molecule Multi-Targeted Kinase Inhibitor RGB-286638 Triggers P53-Dependent and -Independent Anti-Multiple Myeloma Activity through Inhibition of Transcriptional CDKs

Por Cirstea, Diana, Hideshima, Teru, Santo, Loredana, Eda, Homare, Mishima, Yuko, Nemani, Neeharika, Hu, Yiguo, Mimura, Naoya, Cottini, Francesca, Gorgun, Gullu, Ohguchi, Hiroto, Suzuki, Rikio, Loferer, Hannes, Munshi, Nikhil C., Anderson, Kenneth C., Raje, Noopur
Publicado em 2013

A Case of Composite Lymphoma with Extranodal NK/T-cell Lymphoma, Nasal-type and Diffuse Large B-cell Lymphoma

Por Kawai, Hidetsugu, Matsushita, Hiromichi, Kawakami, Shohei, Furuya, Daisuke, Shiraiwa-Hara, Sawako, Ichiki, Akifumi, Hara, Ryujiro, Aoyama, Yasuyuki, Ogiya, Daisuke, Suzuki, Rikio, Machida, Shinichiro, Onizuka, Makoto, Shirasugi, Yukari, Ogawa, Yoshiaki, Kawada, Hiroshi, Nakamura, Naoya, Ando, Kiyoshi
Publicado no J Clin Exp Hematop (2019)

Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma

Por Minami, Jiro, Suzuki, Rikio, Mazitschek, Ralph, Gorgun, Gullu, Ghosh, Balaram, Cirstea, Diana, Hu, Yiguo, Mimura, Naoya, Ohguchi, Hiroto, Cottini, Francesca, Jakubikova, Jana, Munshi, Nikhil C., Haggarty, Stephen J., Richardson, Paul G., Hideshima, Teru, Anderson, Kenneth C.
Publicado em 2013

Antitumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma

Por Suzuki, Rikio, Hidehsima, Teru, Mimura, Naoya, Minami, Jiro, Ohguchi, Hiroto, Kikuchi, Shohei, Yoshida, Yasuhiro, Gorgun, Gullu, Cirstea, Diana, Cottini, Francesca, Jakubikova, Jana, Tai, Yu-Tzu, Chauhan, Dharminder, Richardson, Paul G., Munshi, Nikhil, Utsugi, Teruhiro, Anderson, Kenneth C.
Publicado no Leukemia (2014)

Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition

Por Mimura, Naoya, Hideshima, Teru, Shimomura, Toshiyasu, Suzuki, Rikio, Ohguchi, Hiroto, Rizq, Ola, Kikuchi, Shohei, Yoshida, Yasuhiro, Cottini, Francesca, Jakubikova, Jana, Cirstea, Diana, Gorgun, Gullu, Minami, Jiro, Tai, Yu-Tzu, Richardson, Paul G., Utsugi, Teruhiro, Iwama, Atsushi, Anderson, Kenneth C.
Publicado em 2014

Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells

Por Suzuki, Rikio, Kikuchi, Shohei, Harada, Takeshi, Mimura, Naoya, Minami, Jiro, Ohguchi, Hiroto, Yoshida, Yasuhiro, Sagawa, Morihiko, Gorgun, Gullu, Cirstea, Diana, Cottini, Francesca, Jakubikova, Jana, Tai, Yu-Tzu, Chauhan, Dharminder, Richardson, Paul G., Munshi, Nikhil, Ando, Kiyoshi, Utsugi, Teruhiro, Hideshima, Teru, Anderson, Kenneth C.
Publicado no PLoS One (2015)

The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival

Por Ohguchi, Hiroto, Hideshima, Teru, Bhasin, Manoj K., Gorgun, Gullu T., Santo, Loredana, Cea, Michele, Samur, Mehmet K., Mimura, Naoya, Suzuki, Rikio, Tai, Yu-Tzu, Carrasco, Ruben D., Raje, Noopur, Richardson, Paul G., Munshi, Nikhil C., Harigae, Hideo, Sanda, Takaomi, Sakai, Juro, Anderson, Kenneth C.
Publicado no Nat Commun (2016)

Impact of CD56 Continuously Recognizable as Prognostic Value of Acute Promyelocytic Leukemia: Results of Multivariate Analyses in the Japan Adult Leukemia Study Group (JALSG)-APL20...

Por Takeshita, Akihiro, Asou, Norio, Atsuta, Yoshiko, Furumaki, Hiroaki, Sakura, Toru, Ueda, Yasunori, Sawa, Masashi, Dobashi, Nobuaki, Taniguchi, Yasuhiro, Suzuki, Rikio, Nakagawa, Masaru, Tamaki, Shigehisa, Hagihara, Maki, Fujimaki, Katsumichi, Minamiguchi, Hitoshi, Fujita, Hiroyuki, Yanada, Masamitsu, Maeda, Yoshinobu, Usui, Noriko, Kobayashi, Yukio, Kiyoi, Hitoshi, Ohtake, Shigeki, Matsumura, Itaru, Naoe, Tomoki, Miyazaki, Yasushi
Publicado no Cancers (Basel) (2020)

Lenalidomide Enhances Immune Checkpoint Blockade Induced Immune Response in Multiple Myeloma

Por Görgün, Güllü Topal, Samur, Mehmet K., Cowens, Kristen B., Paula, Steven, Bianchi, Giada, Anderson, Julie E., White, Randie E., Singh, Ahaana, Ohguchi, Hiroto, Suzuki, Rikio, Kikuchi, Shohei, Harada, Takeshi, Hideshima, Teru, Tai, Yu-Tzu, Laubach, Jacob P., Raje, Noopur, Magrangeas, Florence, Minvielle, Stephane, Avet-Loiseau, Herve, Munshi, Nikhil C., Dorfman, David M., Richardson, Paul G., Anderson, Kenneth C.
Publicado no Clin Cancer Res (2015)