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Karyotypic “state” as a potential determinant for anticancer drug discovery

Cancer is a genetic disease caused by genomic instability. In many cancers, this instability is manifested by chromosomal reconfigurations and karyotypic complexity. These features are particular hallmarks of the epithelial cancers that are some of the malignancies most resistant to long term contro...

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Detalhes bibliográficos
Main Authors: Roschke, Anna V., Lababidi, Samir, Tonon, Giovanni, Gehlhaus, Kristen S., Bussey, Kimberly, Weinstein, John N., Kirsch, Ilan R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549443/
https://ncbi.nlm.nih.gov/pubmed/15703300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405578102
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