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Karyotypic “state” as a potential determinant for anticancer drug discovery

Cancer is a genetic disease caused by genomic instability. In many cancers, this instability is manifested by chromosomal reconfigurations and karyotypic complexity. These features are particular hallmarks of the epithelial cancers that are some of the malignancies most resistant to long term contro...

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Autors principals: Roschke, Anna V., Lababidi, Samir, Tonon, Giovanni, Gehlhaus, Kristen S., Bussey, Kimberly, Weinstein, John N., Kirsch, Ilan R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549443/
https://ncbi.nlm.nih.gov/pubmed/15703300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405578102
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