Structural basis for PHD(V)C5HCH(NSD1)–C2HR(Nizp1) interaction: implications for Sotos syndrome

Sotos syndrome is an overgrowth syndrome caused by mutations within the functional domains of NSD1 gene coding for NSD1, a multidomain protein regulating chromatin structure and gene expression. In particular, PHD(V)C5HCH(NSD1) tandem domain, composed by a classical (PHD(V)) and an atypical (C5HCH)...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Berardi, Andrea, Quilici, Giacomo, Spiliotopoulos, Dimitrios, Corral-Rodriguez, Maria Angeles, Martin-Garcia, Fernando, Degano, Massimo, Tonon, Giovanni, Ghitti, Michela, Musco, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838375/
https://ncbi.nlm.nih.gov/pubmed/26896805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw103
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