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Nizp1, a Novel Multitype Zinc Finger Protein That Interacts with the NSD1 Histone Lysine Methyltransferase through a Unique C2HR Motif

Haploinsufficiency of the NSD1 gene is a hallmark of Sotos syndrome, and rearrangements of this gene by translocation can cause acute myeloid leukemia. The NSD1 gene product is a SET-domain histone lysine methyltransferase that has previously been shown to interact with nuclear receptors. We describ...

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Autors principals: Nielsen, Anders Lade, Jørgensen, Poul, Lerouge, Thierry, Cerviño, Margarita, Chambon, Pierre, Losson, Régine
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC419876/
https://ncbi.nlm.nih.gov/pubmed/15169884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5184-5196.2004
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