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In silico derived small molecules targeting the finger-finger interaction between the histone lysine methyltransferase NSD1 and Nizp1 repressor

PHD fingers are small chromatin binding domains, that alone or in tandem work as versatile interaction platforms for diversified activities, ranging from the decoding of the modification status of histone tails to the specific recognition of non-histone proteins. They play a crucial role in their ho...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Berardi, Andrea, Ghitti, Michela, Quilici, Giacomo, Musco, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736721/
https://ncbi.nlm.nih.gov/pubmed/33363704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.11.044
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