H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing

DNA replication is a tightly regulated process that initiates from multiple replication origins and leads to the faithful transmission of the genetic material. For proper DNA replication, the chromatin surrounding origins needs to be remodeled. However, remarkably little is known on which epigenetic...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Rondinelli, Beatrice, Schwerer, Hélène, Antonini, Elena, Gaviraghi, Marco, Lupi, Alessio, Frenquelli, Michela, Cittaro, Davide, Segalla, Simona, Lemaitre, Jean-Marc, Tonon, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357704/
https://ncbi.nlm.nih.gov/pubmed/25712104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv090
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