Identification of AML1-ETO modulators by chemical genomics

Somatic rearrangements of transcription factors are common abnormalities in the acute leukemias. With rare exception, however, the resultant protein products have remained largely intractable as pharmacologic targets. One example is AML1-ETO, the most common translocation reported in acute myeloid l...

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Détails bibliographiques
Auteurs principaux: Corsello, Steven M., Roti, Giovanni, Ross, Kenneth N., Chow, Kwan T., Galinsky, Ilene, DeAngelo, Daniel J., Stone, Richard M., Kung, Andrew L., Golub, Todd R., Stegmaier, Kimberly
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699238/
https://ncbi.nlm.nih.gov/pubmed/19377049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-166090
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