Identification of AML1-ETO modulators by chemical genomics

Somatic rearrangements of transcription factors are common abnormalities in the acute leukemias. With rare exception, however, the resultant protein products have remained largely intractable as pharmacologic targets. One example is AML1-ETO, the most common translocation reported in acute myeloid l...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Corsello, Steven M., Roti, Giovanni, Ross, Kenneth N., Chow, Kwan T., Galinsky, Ilene, DeAngelo, Daniel J., Stone, Richard M., Kung, Andrew L., Golub, Todd R., Stegmaier, Kimberly
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2009
विषय:
Myeloid Neoplasia
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699238/
https://ncbi.nlm.nih.gov/pubmed/19377049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-166090
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