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Structure of the AML1-ETO eTAFH domain–HEB peptide complex and its contribution to AML1-ETO activity
AML1-ETO is the chimeric protein product of the t(8;21) in acute myeloid leukemia. The ETO portion of the fusion protein includes the eTAFH domain, which is homologous to several TATA binding protein–associated factors (TAFs) and interacts with E proteins (E2A and HEB). It has been proposed that AML...
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Prif Awduron: | , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
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American Society of Hematology
2009
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668852/ https://ncbi.nlm.nih.gov/pubmed/19204326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-161307 |
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