Smac mimetics: implications for enhancement of targeted therapies in leukemia: Treating leukemia with Smac mimetics

Drug resistance is a growing concern with clinical use of tyrosine kinase inhibitors. Utilizing in vitro models of intrinsic drug resistance and stromal-mediated chemoresistance, as well as functional mouse models of progressive and residual disease, we attempted to develop a potential therapeutic a...

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Detalhes bibliográficos
Main Authors: Weisberg, Ellen, Ray, Arghya, Barrett, Rosemary, Nelson, Erik, Christie, Amanda, Porter, Dale, Straub, Christopher, Zawel, Leigh, Daley, John F., Lazo-Kallanian, Suzan, Stone, Richard, Galinsky, Ilene, Frank, David, Kung, Andrew L., Griffin, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037865/
https://ncbi.nlm.nih.gov/pubmed/20844561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.212
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