Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem Cells

Por Pandolfi, Ashley, Barreyro, Laura, Steidl, Ulrich
Publicado em 2013

Chronic immune response dysregulation in MDS pathogenesis

Por Barreyro, Laura, Chlon, Timothy M., Starczynowski, Daniel T.
Publicado no Blood (2018)

Deconstructing innate immune signaling in Myelodysplastic Syndromes

Por Varney, Melinda E., Melgar, Katelyn, Niederkorn, Madeline, Smith, Molly, Barreyro, Laura, Starczynowski, Daniel T.
Publicado no Exp Hematol (2015)

Molecular determinants and thermodynamics of the amyloid precursor protein transmembrane domain implicated in Alzheimer's disease

Por Wang, Hao, Barreyro, Laura, Provasi, Davide, Djemil, Imane, Torres-Arancivia, Celia, Filizola, Marta, Ubarretxena-Belandia, Iban
Publicado em 2011

Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation

Por Roth, Michael, Will, Britta, Simkin, Guillermo, Narayanagari, Swathi, Barreyro, Laura, Bartholdy, Boris, Tamari, Roni, Mitsiades, Constantine S., Verma, Amit, Steidl, Ulrich
Publicado em 2012

H2.0-like homeobox (HLX) regulates early hematopoiesis and promotes acute myeloid leukemia

Por Kawahara, Masahiro, Pandolfi, Ashley, Bartholdy, Boris, Barreyro, Laura, Will, Britta, Roth, Michael, Okoye-Okafor, Ujunwa C., Todorova, Tihomira I., Figueroa, Maria E., Melnick, Ari, Mitsiades, Constantine S., Steidl, Ulrich
Publicado em 2012

HSC commitment–associated epigenetic signature is prognostic in acute myeloid leukemia

Por Bartholdy, Boris, Christopeit, Maximilian, Will, Britta, Mo, Yongkai, Barreyro, Laura, Yu, Yiting, Bhagat, Tushar D., Okoye-Okafor, Ujunwa C., Todorova, Tihomira I., Greally, John M., Levine, Ross L., Melnick, Ari, Verma, Amit, Steidl, Ulrich
Publicado em 2014

IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

Por Schinke, Carolina, Giricz, Orsolya, Li, Weijuan, Shastri, Aditi, Gordon, Shanisha, Barreyro, Laura, Bhagat, Tushar, Bhattacharyya, Sanchari, Ramachandra, Nandini, Bartenstein, Matthias, Pellagatti, Andrea, Boultwood, Jacqueline, Wickrema, Amittha, Yu, Yiting, Will, Britta, Wei, Sheng, Steidl, Ulrich, Verma, Amit
Publicado no Blood (2015)

IL1RAP potentiates multiple oncogenic signaling pathways in AML

Por Mitchell, Kelly, Barreyro, Laura, Todorova, Tihomira I., Taylor, Samuel J., Antony-Debré, Iléana, Narayanagari, Swathi-Rao, Carvajal, Luis A., Leite, Joana, Piperdi, Zubair, Pendurti, Gopichand, Mantzaris, Ioannis, Paietta, Elisabeth, Verma, Amit, Gritsman, Kira, Steidl, Ulrich
Publicado no J Exp Med (2018)

Satb1 regulates hematopoietic stem cell self-renewal by promoting quiescence and repressing differentiation commitment

Por Will, Britta, Vogler, Thomas O., Bartholdy, Boris, Garrett-Bakelman, Francine, Mayer, Jillian, Barreyro, Laura, Pandolfi, Ashley, Todorova, Tihomira I., Okoye-Okafor, Ujunwa C., Stanley, Robert F., Bhagat, Tushar D., Verma, Amit, Figueroa, Maria E., Melnick, Ari, Roth, Michael, Steidl, Ulrich
Publicado em 2013

Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia

Por Will, Britta, Vogler, Thomas O., Narayanagari, Swathi, Bartholdy, Boris, Todorova, Tihomira I., da Silva Ferreira, Mariana, Chen, Jiahao, Yu, Yiting, Mayer, Jillian, Barreyro, Laura, Carvajal, Luis, Ben Neriah, Daniela, Roth, Michael, van Oers, Johanna, Schaetzlein, Sonja, McMahon, Christine, Edelmann, Winfried, Verma, Amit, Steidl, Ulrich
Publicado no Nat Med (2015)

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

Por Barreyro, Laura, Will, Britta, Bartholdy, Boris, Zhou, Li, Todorova, Tihomira I., Stanley, Robert F., Ben-Neriah, Susana, Montagna, Cristina, Parekh, Samir, Pellagatti, Andrea, Boultwood, Jacqueline, Paietta, Elisabeth, Ketterling, Rhett P., Cripe, Larry, Fernandez, Hugo F., Greenberg, Peter L., Tallman, Martin S., Steidl, Christian, Mitsiades, Constantine S., Verma, Amit, Steidl, Ulrich
Publicado em 2012

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

Por Will, Britta, Zhou, Li, Vogler, Thomas O., Ben-Neriah, Susanna, Schinke, Carolina, Tamari, Roni, Yu, Yiting, Bhagat, Tushar D., Bhattacharyya, Sanchari, Barreyro, Laura, Heuck, Christoph, Mo, Yonkai, Parekh, Samir, McMahon, Christine, Pellagatti, Andrea, Boultwood, Jacqueline, Montagna, Cristina, Silverman, Lewis, Maciejewski, Jaroslaw, Greally, John M., Ye, B. Hilda, List, Alan F., Steidl, Christian, Steidl, Ulrich, Verma, Amit
Publicado em 2012

Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

Por Shih, Alan H., Jiang, Yanwen, Meydan, Cem, Shank, Kaitlyn, Pandey, Suveg, Barreyro, Laura, Antony-Debre, Ileana, Viale, Agnes, Socci, Nicholas, Sun, Yongming, Robertson, Alexander, Cavatore, Magali, de Stanchina, Elisa, Hricik, Todd, Rapaport, Franck, Woods, Brittany, Wei, Chen, Hatlen, Megan, Baljevic, Muhamed, Nimer, Stephen D., Tallman, Martin, Paietta, Elisabeth, Cimmino, Luisa, Aifantis, Iannis, Steidl, Ulrich, Mason, Chris, Melnick, Ari, Levine, Ross L.
Publicado no Cancer Cell (2015)

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia

Por Okoye-Okafor, Ujunwa C., Bartholdy, Boris, Cartier, Jessy, Gao, Enoch, Pietrak, Beth, Rendina, Alan R., Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J., Reif, Alexander J., Schmidt, Stanley J., Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-Rao, Antony-Debre, Ileana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D., Schwartz, Benjamin, McCabe, Michael T., Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich
Publicado no Nat Chem Biol (2015)