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HSC commitment–associated epigenetic signature is prognostic in acute myeloid leukemia
Acute myeloid leukemia (AML) is characterized by disruption of HSC and progenitor cell differentiation. Frequently, AML is associated with mutations in genes encoding epigenetic modifiers. We hypothesized that analysis of alterations in DNA methylation patterns during healthy HSC commitment and diff...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934187/ https://ncbi.nlm.nih.gov/pubmed/24487588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71264 |
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