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Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation
Eltrombopag (EP) is a small-molecule, nonpeptide thrombopoietin receptor (TPO-R) agonist that has been approved recently for the treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpura. Prior studies have shown that EP stimulates megakaryopoiesis in BM cells from patie...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398759/ https://ncbi.nlm.nih.gov/pubmed/22627766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-399667 |
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