Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

Even though hematopoietic stem cell (HSC) dysfunction is presumed in myelodysplastic syndrome (MDS), the exact nature of quantitative and qualitative alterations is unknown. We conducted a study of phenotypic and molecular alterations in highly fractionated stem and progenitor populations in a varie...

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Detalhes bibliográficos
Main Authors: Will, Britta, Zhou, Li, Vogler, Thomas O., Ben-Neriah, Susanna, Schinke, Carolina, Tamari, Roni, Yu, Yiting, Bhagat, Tushar D., Bhattacharyya, Sanchari, Barreyro, Laura, Heuck, Christoph, Mo, Yonkai, Parekh, Samir, McMahon, Christine, Pellagatti, Andrea, Boultwood, Jacqueline, Montagna, Cristina, Silverman, Lewis, Maciejewski, Jaroslaw, Greally, John M., Ye, B. Hilda, List, Alan F., Steidl, Christian, Steidl, Ulrich, Verma, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437595/
https://ncbi.nlm.nih.gov/pubmed/22753872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-399683
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