Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer

5-hydroxymethylcytosine (5-hmC) is a recently discovered epigenetic modification that is altered in cancers. Genome-wide assays for 5-hmC determination are needed as many of the techniques for 5-methylcytosine (5-mC) determination, including methyl-sensitive restriction digestion and bisulfite seque...

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Main Authors: Bhattacharyya, Sanchari, Yu, Yiting, Suzuki, Masako, Campbell, Nathaniel, Mazdo, Jozef, Vasanthakumar, Aparna, Bhagat, Tushar D., Nischal, Sangeeta, Christopeit, Maximilian, Parekh, Samir, Steidl, Ulrich, Godley, Lucy, Maitra, Anirban, Greally, John M., Verma, Amit
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763560/
https://ncbi.nlm.nih.gov/pubmed/23861445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt601
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